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DS2
$344 – $550
Products Details
Product Description
– DS2 is a selective positive allosteric modulator of δ-GABAA receptor. DS2 selectively potentiates GABA responses mediated by α4β3δ receptor. DS2 does not enhance activity at α4β3γ2 and α1β3γ2 receptors. DS2 relieves pain and has the potential for sleep disorders research[1].
Web ID
– HY-103520
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C18H12ClN3OS
References
– [1]K A Wafford, et al. Novel compounds selectively enhance delta subunit containing GABA A receptors and increase tonic currents in thalamus. Neuropharmacology. 2009 Jan;56(1):182-9.
CAS Number
– 374084-31-8
Molecular Weight
– 353.83
SMILES
– O=C(NC1=C(C2=CC=CS2)N=C3C=CC=CN31)C4=CC=C(Cl)C=C4
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– GABA Receptor
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
