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DDR1-IN-5
$480 – $3,600
Products Details
Product Description
– DDR1-IN-5 is a selective Discoidin Domain Receptor family, member 1 (DDR1) inhibitor with an IC50 of 7.36 nM. DDR1-IN-5 inhibits auto-phosphorylation DDR1b (Y513) with an IC50 of 4.1 nM. DDR1-IN-5 has anti-cancer activity[1]. DDR1-IN-5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Web ID
– HY-133669
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture and light)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C22H13F3N6O
References
– [1]Aleksandr M. Aliper, et al. Kinase inhibitors. WO2020079652A1.
CAS Number
– 2416022-90-5
Molecular Weight
– 434.37
Compound Purity
– 99.27
SMILES
– CC1=C(C#CC2=CN=C3N2N=CC=C3)C4=C(C=C1)C(NC5=CN=CC(C(F)(F)F)=C5)=NO4
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 2.78 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Discoidin Domain Receptor
Isoform
– DDR1
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
