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D-Lin-MC3-DMA
$100 – $800
Products Details
Product Description
– D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle.
Web ID
– HY-112251
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C43H79NO2
References
– [1]Kulkarni JA, et al. Design of lipid nanoparticles for in vitro and in vivo delivery of plasmid DNA. Nanomedicine. 2017 May;13(4):1377-1387.|[2]Ferraresso F, Strilchuk AW, Juang LJ, Poole LG, Luyendyk JP, Kastrup CJ. Comparison of DLin-MC3-DMA and ALC-0315 for siRNA Delivery to Hepatocytes and Hepatic Stellate Cells. Mol Pharm. 2022;19(7):2175-2182.
CAS Number
– 1224606-06-7
Molecular Weight
– 642.09
Compound Purity
– 99.83
SMILES
– O=C(OC(CCCCCCCC/C=CC/C=CCCCCC)CCCCCCCC/C=CC/C=CCCCCC)CCCN(C)C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic)|Ethanol : 125 mg/mL (ultrasonic)
Target
– Liposome
Pathway
– Metabolic Enzyme/Protease
Product type
– Oligonucleotides
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
