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Products Details
Product Description
– CYP3A4 enzyme-IN-1 (compound 59) is a potent antibacterial agent, with a MIC of 1 μg/mL for MRSA. CYP3A4 enzyme-IN-1 exhibits low to moderate inhibitory effects on CYP1A2, CYP2E1, CYP2D6, and CYP3A4 enzymes[1].
Web ID
– HY-146177
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C41H58N8O7
References
– [1]Zhang GY, et, al. Design, synthesis and biological evaluation of novel pleuromutilin derivatives containing piperazine and 1,2,3-triazole linker. Bioorg Chem. 2020 Dec;105:104398.
CAS Number
– 2531281-25-9
Molecular Weight
– 774.95
SMILES
– C[C@@H]1[C@]23[C@](C(CC3)=O)([H])[C@]([C@@H](C[C@](C)([C@H]1O)C=C)OC(CN4CCN(CC4)C(CN5C=C(N=N5)CN6CCN(C7=CC=C(C=C7)[N+]([O-])=O)CC6)=O)=O)([C@@H](CC2)C)C
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Bacterial;Cytochrome P450
Isoform
– CYP1;CYP2;CYP3
Pathway
– Anti-infection;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
