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CRT0105950
SKU
HY-120025-10 mg
Category Reference compound
Tags Cancer, Cell Cycle/DNA Damage, LIM Kinase (LIMK)
$175 – $1,440
Products Details
Product Description
– CRT0105950 is a potent LIMK inhibitor, with IC50s of 0.3 nM and 1 nM for LIMK1 and LIMK2 respectively. CRT0105950 can be used for the research of cancer[1].
Web ID
– HY-120025
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C21H16ClN3OS
References
– [1]Mardilovich K, et, al. LIM kinase inhibitors disrupt mitotic microtubule organization and impair tumor cell proliferation. Oncotarget. 2015 Nov 17;6(36):38469-86.
CAS Number
– 1661845-86-8
Molecular Weight
– 393.89
Compound Purity
– 99.91
SMILES
– OC1=CC=C(C=C1)NC2=NC=C(S2)C3=C(C=NC=C3)C4=CC=C(C=C4Cl)C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 250 mg/mL (ultrasonic)
Target
– LIM Kinase (LIMK)
Isoform
– LIMK1;LIMK2
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.