CRT0105950

$175$1,440

Products Details

Product Description

– CRT0105950 is a potent LIMK inhibitor, with IC50s of 0.3 nM and 1 nM for LIMK1 and LIMK2 respectively. CRT0105950 can be used for the research of cancer[1].

Web ID

– HY-120025

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Cancer-Kinase/protease

Molecular Formula

– C21H16ClN3OS

References

– [1]Mardilovich K, et, al. LIM kinase inhibitors disrupt mitotic microtubule organization and impair tumor cell proliferation. Oncotarget. 2015 Nov 17;6(36):38469-86.

CAS Number

– 1661845-86-8

Molecular Weight

– 393.89

Compound Purity

– 99.91

SMILES

– OC1=CC=C(C=C1)NC2=NC=C(S2)C3=C(C=NC=C3)C4=CC=C(C=C4Cl)C

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– DMSO : 250 mg/mL (ultrasonic)

Target

– LIM Kinase (LIMK)

Isoform

– LIMK1;LIMK2

Pathway

– Cell Cycle/DNA Damage

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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