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CPS2
$190 – $2,350
Products Details
Product Description
– CPS2 is a first-in-class, highly potent, selective and irreversible PROTAC CDK2 degrader (IC50= 24 nM). CPS2 can be used for the research of acute myeloid leukemia[1].
Web ID
– HY-141680
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C38H42N12O10S2
References
– [1]Wang L, et al. Discovery of a first-in-class CDK2 selective degrader for AML differentiation therapy. Nat Chem Biol. 2021;17(5):567-575
CAS Number
– 2756741-90-7
Molecular Weight
– 890.94
Compound Purity
– 99.33
SMILES
– O=C(N1)CCC(N2C(C3=CC=CC(NCCOCCOCCN4N=NC(COCCNS(C5=CC=C(C=C5)NC6=NN(C(N)=N6)C(C7=C(C=CS7)C)=O)(=O)=O)=C4)=C3C2=O)=O)C1=O
Clinical Information
– Phase 1
Research Area
– Cancer
Solubility
– DMSO : 32.5 mg/mL (ultrasonic)
Target
– CDK
Isoform
– CDK2
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
