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Products Details
Product Description
– CLK1/2-IN-2 is CLK1 and CLK2 inhibitor with IC50 values of 16 nM and 45 nM, respectively. CLK1/2-IN-2 exhibits potent anti-cancer activities[1].
Web ID
– HY-113825
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C21H20F3N7O
References
– [1]Shinsuke Araki, et al. Inhibitors of CLK protein kinases suppress cell growth and induce apoptosis by modulating pre-mRNA splicing. PLoS One
CAS Number
– 1005784-23-5
Molecular Weight
– 443.43
SMILES
– O=C(NC1=CN2C=C(C(F)(F)F)C=CC2=N1)C3=CC=C(C(C)(C)CCC4=NNN=N4)C=C3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– CDK
Isoform
– CLK
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
