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Product Description
– CL4F8-6 is an ionizable cationic lipid with a pKa of 6.14. CL4F8-6 can be used in lipid nanoparticles (LNPs)-based mRNA therapeutics. CL4F8-6 LNPs carrying Cas9 mRNA and sgRNA could induce CRISPR-mediated gene knockdown in mice[1].
Web ID
– HY-157252
Shipping
– Room temperature
Molecular Formula
– C51H101NO5
References
– [1]Kazuki Hashiba, et al. Branching Ionizable Lipids Can Enhance the Stability, Fusogenicity, and Functional Delivery of mRNA. Small Science. 09 November 2022.
CAS Number
– 2766493-12-1
Molecular Weight
– 808.35
SMILES
– O=C(C(CCCCCC)CCCCCC)OCCCCCCC(CCCCN(CCC)CCC)(CCCCCCOC(C(CCCCCC)CCCCCC)=O)O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Liposome
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
