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CHMFL-KIT-033
$315
Only 1000 item(s) left in stock.
Products Details
Product Description
– CHMFL-KIT-033 is a potent and selective inhibitor of c-KIT T670I mutant for gastrointestinal stromal tumors (GISTs), with an IC50 of 0.045 μM[1].
Web ID
– HY-128589
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C23H18FN5O2
References
– [1]Liu X, et al. Discovery of ( E)- N1-(3-Fluorophenyl)- N3-(3-(2-(pyridin-2-yl)vinyl)-1 H-indazol-6-yl)malonamide (CHMFL-KIT-033) as a Novel c-KIT T670I Mutant Selective Kinase Inhibitor for Gastrointestinal Stromal Tumors (GISTs). J Med Chem. 2019 May 23;62(10):5006-5024.
CAS Number
– 2351801-41-5
Molecular Weight
– 415.42
SMILES
– O=C(CC(NC1=CC=CC(F)=C1)=O)NC2=CC(NN=C3/C=C/C4=CC=CC=N4)=C3C=C2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– c-Kit
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
