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Products Details
Product Description
– CDK9-IN-14 is a potent and selective CDK9 inhibitor with IC50 of 6.92 nM. CDK9-IN-14 has a relatively strong inhibitory effect on MV4;11 cells and in vivo tumor models, and has a good selectivity and a low toxicity and few side effects[1].
Web ID
– HY-143585
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C21H23F2N3O4
References
– [1]WANG Zhenyu. Compound as cyclin-dependent kinase 9 inhibitor and use thereof. WO2021115335A1
CAS Number
– 2650640-17-6
Molecular Weight
– 419.42
SMILES
– O=C([C@@H]1C[C@H](NC(CO)=O)CCC1)NC2=NC=C(F)C(C3=CC=C(F)C=C3OC)=C2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– CDK
Isoform
– CDK9
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
