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Products Details
Product Description
– Caspase-3 activator 3 (compound 2h) induces apoptosis in HL-60 and K562 cells via significant caspase 3 activation. Caspase-3 activator 3 shows antileukemic acticity against HL-60 and K562 cells, with IC50 values of 42.89 and 33.61 μM, respectively[1].
Web ID
– HY-155390
Shipping
– Room temperature
Molecular Formula
– C24H25BrN4S
References
– [1]Mehlika Dilek Altıntop, et al. Design, Synthesis, and Evaluation of a New Series of 2-Pyrazolines as Potential Antileukemic Agents. ACS Omega 2023.
Molecular Weight
– 481.45
SMILES
– CN1CCN(C2=CC=C(C3CC(C4=CSC=C4)=NN3C5=CC=CC(Br)=C5)C=C2)CC1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;Caspase
Isoform
– Caspase 3
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
