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Products Details
Product Description
– BMS-684 is a selective and potent DGKα inhibitor (IC50: 15 nM) with potential antitumor activity.BMS-684 inhibits DGKα kinase, DGKβ, and DGKγ.BMS-684 activates T-cells, which may prevent and treat immune-related diseases.
Web ID
– T77760
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C27H26N4O3
References
– Michael Wichroski, et al. DGKα/ζ inhibitors combine with PD-1 checkpoint therapy to promote T cell-mediated antitumor immunity. Sci Transl Med. 2023 Oct 25;15(719):eadh1892.
CAS Number
– 313552-29-3
Molecular Weight
– C27H26N4O3
Compound Purity
– 0.9975
SMILES
– O=C1C([N+]([O-])=O)=C(N2CCN(C(C3=CC=CC=C3)C4=CC=CC=C4)CC2)C5=C(N1C)C=CC=C5
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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