Download Files:
Products Details
Product Description
– Balsalazide sodium hydrate could suppress colitis-associated carcinogenesis through modulation of IL-6/STAT3 pathway.
Web ID
– HY-B0667A
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C17H17N3Na2O8
References
– [1]Do EJ, et al. Suppression of colitis-associated carcinogenesis through modulation of IL-6/STAT3 pathway by balsalazide and VSL#3. J Gastroenterol Hepatol. 2016 Aug;31(8):1453-61.|[2]Kruis W, et al. Low dose balsalazide (1.5 g twice daily) and mesalazine (0.5 g three times daily) maintained remission of ulcerative colitis but high dose balsalazide (3.0 g twice daily) was superior in preventing relapses. Gut, 2001. 49(6): p. 783-789.
CAS Number
– 150399-21-6
Molecular Weight
– 437.31
SMILES
– O=C(O)C1=CC(/N=N/C2=CC=C(C(NCCC(O[Na])=O)=O)C=C2)=CC=C1O[Na].O.O
Clinical Information
– Launched
Research Area
– Inflammation/Immunology; Cancer
Solubility
– 10 mM in H2O
Target
– Interleukin Related;STAT
Isoform
– IL-1;IL-6;STAT3
Pathway
– Immunology/Inflammation;JAK/STAT Signaling;Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
