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BAI1
$100 – $950
Products Details
Product Description
– BAI1 is a selective and allosteric inhibitor of BAX, an apoptosis regulator. BAI1 directly binds to BAX and allosterically inhibits BAX activation. BAI1 has the potential for the research of diseases mediated by BAX-dependent cell death[1].
Web ID
– HY-103269
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C19H21Br2N3O
References
– [1]Garner TP, et al. Small-molecule allosteric inhibitors of BAX. Nat Chem Biol. 2019 Apr;15(4):322-330.
CAS Number
– 335165-68-9
Molecular Weight
– 467.20
Compound Purity
– 99.73
SMILES
– OC(CN1CCNCC1)CN2C3=C(C4=C2C=CC(Br)=C4)C=C(Br)C=C3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 18.67 mg/mL (ultrasonic)
Target
– Apoptosis;Bcl-2 Family
Isoform
– Bax
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
