Azathioprine

$55$125

Products Details

Product Description

– Azathioprine (BW 57-322) is an orally active immunosuppressive agent. Azathioprine can be converted in vivo to the active metabolite 6-mercaptopurine (6-MP). Azathioprine has myelosuppressive effects and induces apoptosis[1][3].

Web ID

– HY-B0256

Storage Temperature

– 4°C (Powder, protect from light)

Shipping

– Room Temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C9H7N7O2S

References

– [1]Patel, A.A., R.A. Swerlick, and C.O. McCall, Azathioprine in dermatology: the past, the present, and the future. J Am Acad Dermatol, 2006. 55(3): p. 369-89.|[2]Maltzman, J.S. and G.A. Koretzky, Azathioprine: old drug, new actions. J Clin Invest, 2003. 111(8): p. 1122-4.|[3]Dubinsky, M.C., Azathioprine, 6-mercaptopurine in inflammatory bowel disease: pharmacology, efficacy, and safety. Clin Gastroenterol Hepatol, 2004. 2(9): p. 731-43.

CAS Number

– 446-86-6

Molecular Weight

– 277.26

Compound Purity

– 99.98

SMILES

– O=[N+](C1=C(SC2=C3NC=NC3=NC=N2)N(C)C=N1)[O-]

Clinical Information

– Launched

Research Area

– Inflammation/Immunology; Cancer

Solubility

– DMSO : 50 mg/mL (ultrasonic)|H2O : 0.1 mg/mL (ultrasonic)

Target

– Apoptosis

Pathway

– Apoptosis

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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