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Products Details
Product Description
– anti-TNBC agent-1 is a potent anti-triple-negative breast cancer (TNBC) agent. anti-TNBC agent-1 exhibits potent activity against different breast cancer cells with IC50 values ranging from 0.20 μM to 0.27 μM. anti-TNBC agent-1 induces apoptosis of SUM-159 cells through mitochondria pathway and causes G1 phase arrest of SUM-159 cells[1].
Web ID
– HY-145143
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C26H30O7
References
– [1]Ge W, et al. Synthesis and structure-activity relationship studies of parthenolide derivatives as potential anti-triple negative breast cancer agents. Eur J Med Chem. 2019;166:445-469.
CAS Number
– 2289585-58-4
Molecular Weight
– 454.51
SMILES
– C[C@@]1(CC/C=C2COC(/C=C/C(C(OC)=CC=C3)=C3OC)=O)[C@@](O1)([H])[C@](OC4=O)([H])[C@](CC/2)([H])C4=C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis
Pathway
– Apoptosis
Product type
– Reference compound
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