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Products Details
Product Description
– Anti-inflammatory agent 41 (13a) significantly inhibit lipopolysaccharide (LPS)-induced expression of the proinflammatory cytokines IL-6 and TNF-α on J774A.1, THP-1 and LX-2 cells, and inhibits the activation of the NF-κB pathway[1].
Web ID
– HY-149816
Shipping
– Room temperature
Molecular Formula
– C33H25N3O5
References
– [1]Jun Yang, et al. Discovery of 4-oxo-N-phenyl-1,4-dihydroquinoline-3-carboxamide derivatives as novel anti-inflammatory agents for the treatment of acute lung injury and sepsis. Eur J Med Chem. 2023 Mar 5;249:115144.
CAS Number
– 2896204-90-1
Molecular Weight
– 543.57
SMILES
– COC1=CC2=C(C(OC3=CC=C(C=C3)NC(C4=CN(C5=CC=CC=C5C4=O)C6=CC=CC=C6)=O)=CC=N2)C=C1OC
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Interleukin Related;NF-κB;TNF Receptor
Pathway
– Apoptosis;Immunology/Inflammation;NF-κB
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
