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Products Details
Product Description
– Anti-inflammatory agent 20 (compound 5a) is a potent inhibitor of NO activity. Anti-inflammatory agent 20 shows anti-inflammatory activity. Anti-inflammatory agent 20 suppresses LPS-induced inflammation via inhibiting the activation of NF-κB and MAPK signaling and thereby reducing IL-6, TNF-α, iNOS, and COX-2 upregulation[1].
Web ID
– HY-146419
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C39H66N2O8
References
– [1]Yang G, et al. Design, synthesis and anti-inflammatory activity of 3-amino acid derivatives of ocotillol-type sapogenins. Eur J Med Chem. 2020 Sep 15;202:112507.
CAS Number
– 2127403-65-8
Molecular Weight
– 690.95
SMILES
– [H][C@@]12[C@H](CC[C@]1([C@@]3(CC[C@]4(C(C)([C@H](CC[C@@]4([C@]3(C[C@H]2O)[H])C)OC(CNC(CNC(OC(C)(C)C)=O)=O)=O)C)[H])C)C)[C@@]5(CC[C@@H](O5)C(C)(O)C)C
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– COX;NF-κB;TNF Receptor
Isoform
– CD40;COX-2;NF-κB
Pathway
– Apoptosis;Immunology/Inflammation;NF-κB
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
