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Products Details
Product Description
– AM8191 is an orally active bactericidal and selectively inhibits DNA synthesis and Staphylococcus aureus gyrase (IC50=1.02 μM) and topo IV (IC50=10.4 μM). AM8191 inhibits S. aureus MSSA (MIC=0.02 μg/mL) and S. aureus MRSA (MIC=0.06 μg/mL)[1].
Web ID
– HY-125424
Shipping
– Room temperature
Molecular Formula
– C26H29ClFN5O5
References
– [1]Sheo B Singh, et al. Oxabicyclooctane-linked novel bacterial topoisomerase inhibitors as broad spectrum antibacterial agents. ACS Med Chem Lett. 2014 Mar 12;5(5):609-14.
CAS Number
– 1417548-17-4
Molecular Weight
– 545.99
SMILES
– O=C1NC2=NC(CNC34CCC(OC3)(CC4)[C@@H](O)CC5=C(F)C=NC6=CC=C(OC)N=C56)=CC=C2OC1.Cl
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Bacterial
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
