Download Files:
AC710
$168 – $1,860
Products Details
Product Description
– AC710 is a potent PDGFR inhibitor with Kds of 0.6, 1.57, 1, 1.3, 1.0 nM for FLT3, CSF1R, KIT, PDGFRα and PDGFRβ, respectively.
Web ID
– HY-13493
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C31H42N6O4
References
– [1]Liu G, et al. Discovery of AC710, a Globally Selective Inhibitor of Platelet-Derived Growth Factor Receptor-Family Kinases. ACS Med Chem Lett. 2012 Sep 24;3(12):997-1002.
CAS Number
– 1351522-04-7
Molecular Weight
– 562.70
Compound Purity
– 98.56
SMILES
– O=C(C1=NC=C(OC2CC(C)(C)N(CC)C(C)(C)C2)C=C1)NC3=CC=C(NC(NC4=NOC(C(C)(C)C)=C4)=O)C=C3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 14 mg/mL (ultrasonic;warming)
Target
– c-Kit;FLT3;PDGFR
Isoform
– PDGFRα;PDGFRβ
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
